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ADVACNED ACNE CLEARING SOLUTION
BHA 2% With Nelupure™ and Willow Bark Extract
This effective formula of Beta Hydroxy Acid (salicylic acid) and other potent ingredients significantly clear acne and prevent it from recurring. The anti-inflammatory, anti-microbial and anti-bacterial ingredients combined with BHA work together to reduce swelling, blemishes, clear whiteheads and blackheads and deeply unclog pores affected by the overproduction of sebum oil. In addition, NELUPURE™, another potent ingredient that helps to balance sebum secretion, diminish skin shine and reduce blemishes and imperfections of the skin.
For all skin types
100% Plant based
Beta Hydroxy Acid (BHA)
Beta Hydroxy Acid (BHA) is a clinically proven chemical compound for treating moderate to severe acne skin conditions. BHA significantly clears whiteheads, blackheads and it’s know by it’s anti-bacterial and anti-inflammatory properties. it deeply exfoliates clogged pores and breakdown sebum oil that builds up over time.
Nelupure™ (Nymphaea Caerulea Flower Extract, Nelumbo Nucifera Flower Extract) is an extract of blue and pink lotus flower. the active ingredient reduces the activity of sebum overproduction, helps to balance sebum secretion, diminishes skin shine and reduces blemishes and imperfections of the skin.
Willow Bark Extract
Natural Salicylate, enriched with salicylic derivatives, provides effective anti-blemish, anti-irritant, anti-seborrheic and keratolytic action. It helps break up the oils and remove the flakes, leading to clean pores and oil balanced appearance.
Tea tree oil is proven to treat moderate to severe acne because of its anti-inflammatory, antibacterial, antifungal and antimicrobial properties. The extract is known to reduce swelling and inflammation. it rapidly diminishes active acne. It also helps to prevent acne scarring caused by deep cystic acne.
How to Use?
Apply a dime-sized amount to a clean, dry face once or twice daily. Gently pat into the skin, avoiding the eye area. Recommended to be used after cleansing and toning but before heavy moisturisers. If used during the day it is recommended to apply sunscreen of SPF 30+.
Safety & Precautions
Note: This potent formula contains Beta Hydroxy Acid (BHA). Patch test before use is recommended to avoid skin irritation or burning
Caution: BHA may initially cause redness and irritation, and it should not be combined with retinol or any other Vitamin A derivatives, at least in the beginning of adding BHA to the daily regimen. Once the skin has built tolerance to using BHA, Retinol can be added to the regimen. It is highly recommended not to use BHA and Retinol at the same time. Instead, BHA can be applied in the morning and Retinol at night or one night BHA and the next night Retinol.
Nelupure – Reduces Sebum Secretion by ¯ Lipid Synthesis & Modulation of Gene Expression
An in vitro study found out that Nelupure decreases the gene expression of proteins required for sebum synthesis, like Leptin, CIDEA, PLIN2, PLIN3, and also those responsible for its inflammatory effects i.e. cytokine IL-8. Another comparative study tested the incubation of sebocytes with Nelupure against a placebo control, for 3 days and analyzed the effects on lipid synthesis. 44% reduction of lipid production was observed with Nelupure along with a 47% decrease in the area of lipid droplets.
Salicylic Acid Reduces Acne Score within a few Weeks
During research conducted at the Dermatology Division of Loyola University, Chicago, it was found that by using a salicylic acid peel, the patients’ acne score on GEA (Global Evaluation Acne) Scale dropped by 1.56 within 9 weeks, and this drop was even more (1.61) when the Pulsed Dye Laser (PDL) treatment was aided with this salicylic acid peel (shown in Figure). It was concluded that salicylic acid, even alone, is significantly efficacious and safe for treating moderate to severe acne, and it further augments the efficacy of PDL in this regard.
Significant improvements are seen in >90% of patients with Salicylic Acid within 2 months
Similarly, during a comparative study, carried out at the Assiut University Hospital, Egypt, 30% and 50% of patients with mild acne, and 30% and 40% of patients with moderate acne demonstrated excellent and good improvements, respectively, with the use of salicylic acid peeling for only two months, rest showed fair results, while the percentage frequency of poor results was almost equal to none. This was much better than that of lactic acid peeling used in comparison during this study as shown in the figure.
Tea Tree Oil – Highly effective treatment for acne lesions
Regarding the evaluation of effectiveness and tolerability of using Tea tree oil for the treatment of mild to moderate acne, a pilot study was done in Perth, Australia in which participants were asked to apply tea tree oil twice a day for 12 weeks. The percentage of a total number of facial acne lesions in patients fall by 54% till the end of 12 weeks of usage (as demonstrated in the graph), while no serious adverse effects were observed with its use. Therefore, researchers claimed that tea tree oil products are very beneficial for acne, and are well-tolerated 
1. Lekakh O, Mahoney AM, Novice K, Kamalpour J, Sadeghian A, Mondo D, Kalnicky C, Guo R, Peterson A, Tung R. Treatment of acne vulgaris with salicylic acid chemical peel and pulsed dye laser: a split face, rater-blinded, randomized controlled trial. Journal of lasers in medical sciences. 2015;6(4):167.
4. Malhi HK, Tu J, Riley TV, Kumarasinghe SP, Hammer KA. Tea tree oil gel for mild to moderate acne; a 12 week uncontrolled, open‐label phase II pilot study. Australasian Journal of Dermatology. 2017 Aug;58(3):205-10.